Semiautomatic method for the ultra-trace arsenic speciation in environmental and biological samples via magnetic solid phase extraction prior to HPLC-ICP-MS determination

A novel magnetic functionalized material based on graphene oxide and nanoparticles (MGO) was used to develop a solid phase extraction method (MSPE) enrich both, inorganic organic arsenic species in environmental waters biological samples. An automatic flow injection (FI) system preconcentrate the simultaneously, while ultra-trace separation determination of arsenobetaine (AsBet), cacodylate, As III V were achieved by high performance liquid chromatography combined with inductively coupled plasma mass spectrometry (HPLC-ICP-MS). The sample introduced FI where MSPE performed, then 1 mL eluent collected chromatographic vial, which autosampler HPLC-ICP-MS. Therefore, preconcentration separation/determination processes conducted separately. To best our knowledge, this is first combining an HPLC-ICP-MS for speciation, using nanomaterial MGO MSPE. Under optimized conditions, LODs 3.8 ng L ?1 AsBet, 0.5 1.1 0.2 RSDs <5%. developed validated analyzing Certified Reference Materials total concentration (fortified lake water TMDA 64.3 seawater CASS-6 NRC) also recovery analysis urine, well-water samples Málaga. has shown promise routine monitoring fluids. • Semiautomatic speciation First analytical MGO-PSTH. proposed very good precision. Drinking water, urine analyzed external calibration. MGO, HPLC speciation.